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Uman Diagnostics simca-p multivariate analysis package software
Simca P Multivariate Analysis Package Software, supplied by Uman Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/analysis+software+simca+p/software+simca+p+ver+11+0/pm38282115-116-36-41
Average 90 stars, based on 1 article reviews
simca-p multivariate analysis package software - by Bioz Stars, 2026-11
90/100 stars

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Article Title: Suppression of up-regulated LXRα by silybin ameliorates experimental rheumatoid arthritis and abnormal lipid metabolism.
Article Snippet: Background: As dysregulation of immunometabolism plays a key role in the immunological diseases, dyslipidemia frequently observed in rheumatoid arthritis (RA) patients (60%) is associated with the disease activity and has been considered as the potential target of anti-inflammatory strategy.. However, targeting of metabolic events to develop novel anti-inflammatory therapeutics are far from clear as well as the mechanism of dysli-

Article Title: Dynamic variations of plasma and urine metabolic profiles in left anterior descending coronary artery ligation-induced myocardial infarction rats and the regulatory effects of Chinese patent medicine Xin-Ke-Shu.
Article Snippet: Myocardial infarction (MI) is one of the most severe cardiovascular diseases (CVD).. Traditional Chinese medicines have unique advantages in the treatment of CVD, with Xin-Ke-Shu (XKS) being a commonly used Chinese patent medicine for the prevention and treatment of MI patients.. This study aimed to investigate the dynamic metabolic profiles of plasma and urine in left anterior descending coronary artery ligation (LAD) -induced MI rats at days 3, 12, and 21 after surgery, and to evaluate the regulatory effects of XKS at these time points using ultraperformance liquid chromatography coupled with quadrupole time-of-flight mass spectrometry (UPLC-Q-TOF/ MS) metabolomics.

Article Title: The lipid homeostasis regulation study of arenobufagin in zebrafish HepG2 xenograft model and HepG2 cells using integrated lipidomics-proteomics approach.
Article Snippet: 16 Ethnopharmacological relevance: Arenobufagin (ArBu) is an important anti-tumor 17 ingredient of Chan’su which has long been used as traditional Chinese medicine in clinic 18 for tumor therapy in China.. 19 Aim of the study: The purpose of our study is to investigate the lipid homeostasis regulation 20 effects of ArBu on zebrafish model of liver cancer and hepatoma cells, and to provide a 21 reference for further clarifying its active mechanisms.. 22 Materials and methods: The zebrafish xenograft model was established by injecting HepG2 23 cells stained with CM-Dil red fluorescent dye.

Article Title: Integrated nutritional and functional components analyses reveal insights into the peel and pulp quality at different harvest times of 'Dahongpao' tangerine (Citrus reticulata Blanco).
Article Snippet: The fruit of Citrus reticulata ‘Dahongpao’ (DHP) is typically harvested when fully ripe, exhibiting a dark red color, high sweetness, and pleasant taste.. However, it remains uncertain whether the optimum harvesting time for its medicinal part (peel) aligns with that of the fruit.. The findings of the study indicated that the peel exhibited the highest concentration of total flavonoids (4.018 mg/g) during the middle stage of maturity.

Article Title: Tanshinone IIA reverses gefitinib resistance in EGFR-mutant lung cancer via inhibition of SREBP1-mediated lipogenesis.
Article Snippet: Funding information Guangdong Provincial Key Laboratory of Construction Foundation, Grant/Award Number: 2020B1212060034; National Natural Science Foundation of China, Grant/Award Numbers: 81973561, 82274146 Abstract Background and Aim: Gefitinib resistance is an urgent problem to be solved in the treatment of non-small cell lung cancer (NSCLC).. Tanshinone IIA (Tan IIA) is one of the main active components of Salvia miltiorrhiza, which exhibits significant antitumor effects.. The aim of this study is to explore the reversal effect of Tan IIA on gefitinib resistance in the epidermal growth factor receptor (EGFR)-mutant NSCLC and the underlying mechanism.

Article Title: Toxicokinetics of Arenobufagin and its Cardiotoxicity Mechanism Exploration Based on Lipidomics and Proteomics Approaches in Rats
Article Snippet: Once the data table was exported and normalized, a multivariate analysis was performed using SIMCA-P 14.0 software (Umetric, Umea, Sweden), including principal components analysis (PCA) and orthogonal projection to latent structures discriminate analysis (OPLS-DA).

Software:

Article Title: Method development of amine‐containing metabolite analysis using di‐<i>tert</i>‐butyl dicarbonate derivatization coupled with liquid chromatography‐mass spectrometry
Article Snippet: .. The integrated area of the metabolite features was normalized to that of an IS, exported as CSV, and subjected to multivariate analysis using SIMCA-P + software (Version 14.0, Umertrics, Umea, Sweden). .. Statistical analysis was performed using GraphPad Prism (version 7.0, SD, USA).



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